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. Author manuscript; available in PMC: 2018 Oct 15.
Published in final edited form as: Acta Biomater. 2017 Sep 1;62:167–178. doi: 10.1016/j.actbio.2017.08.038

Figure 4.

Figure 4

Cellular uptake of GPP-modified polyplex post caveolin-1 silencing. a) Caveolin-1 (cav-1) silencing efficiency was determined 2 days post-treatment via western blots. Expression levels relative to a non-treated control were also examined 1 and 3 days post treatment (Fig. S1). b) Changes in polyplex endocytic pathways mediated by GPP-modification and continued association with collagen fragments were elucidated in caveolin-1 silencing transfection experiments. Each data point represents the mean +/− standard deviation for a total of six separately prepared and analyzed samples.