Table 8.

Overview of search results for tobacco use and LUTS

LUTS Condition Studied	Number articles	Study Design	Population	Results Summary	Comments
BPH17, 45-47, 66-68, 85, 86, 115-117	12	4-Cohort	All Men	Mixed results: 7-NS	Some evidence for negative association, more evidence for no association
		6-Cross- sectional		1- NS, S, +
		2-Case-control
				2- NS, S, -
				2- S, -
Nocturia48, 50, 68-71	6	5-Cross-sectional	3-Women	Mixed results:	Inconsistent results
		1-Cohort	2-Men	2- NS
				1- NS, S, -
				1- S, +
				2- S, -
OAB/LUTS (non-UI)54, 61, 69, 71-74, 85, 86, 95, 109, 111, 113, 118-123	19	18-Cross- sectional	6-Women	Mixed results: 7-NS	Some evidence for a positive association, other evidence shows no association
			11-Men
		1-Cohort
			2- Women and Men	3- NS, S, +
				7- S, +
				2- not reported
UI59, 69, 71, 73, 75-81, 118, 124	13	2-Case- control	All Women	Mixed results: 6-NS	Some evidence for a positive association, other evidence shows no association
		11-Cross- sectional		1- NS, S, +/-
				3- S, +
				1- S, +/-
				2- not reported
Other- UDS & parameters plasma levels82-86	5	1-Case control	2-Women	Mixed results:	Outcomes varied, some evidence of associations
			3- Men
		1-Case series		2- NS, S, +
		3-Cross- sectional		1- S, +
				2- S, -

S = Statistically significant association, NS = Not statistically significant association, + = Positive association, - = Negative association