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. Author manuscript; available in PMC: 2018 Nov 15.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2017 Jul 12;99(4):787–796. doi: 10.1016/j.ijrobp.2017.07.008

Table 2.

Progression-Free Survival and Overall Survival

Randomized arm 55.8 Gy(RBE) 63.0 Gy(RBE) p-value

Progression-Free Survival (95% CI)

Entire Cohort 0.234
  5 years 91% (68–98%) 91% (68–98%)
  10 years 86% (62–95%) 81% (58–93%)
  15 years 52% (28–72%) 70% (45–86%)
  Median (years) 15.6 (12.3–18.0) NR

Subtotal Resection 0.820
  5 years 100%* 83% (48–96%)
  10 years 91% (51–99%) 67% (34–86%)
  15 years 64% (30–85%) 57% (25–80%)
  Median (years) 16.3 (12.3–18.9) 16.3 (4.9-NR)

Recurrent 0.061
  5 years 82% (45–95%) 100%*
  10 years 82% (45–95%) 100%*
  15 years 39% (7–71%) 87% (39–98%)
  Median (years) 13.5 (2.6-NR) NR

Overall Survival (95% CI)

Entire cohort 0.271
  5 years 91% (68–98%) 91% (68–98%)
  10 years 86% (62–95%) 81% (58–93%)
  15 years 62% (35–80%) 75% (50–89%)
  Median (years) 16.3 (13.5–18.9) NR

Subtotal Resection 0.975
  5 years 100%* 83% (48–96%)
  10 years 91% (51–99%) 67% (34–86%)
  15 years 64% (30–85%) 57% (25–80%)
  Median (years) 16.3 (12.3–18.9) 16.3 (4.9-NR)

Recurrent 0.150
  5 years 82% (45–95%) 100%*
  10 years 82% (45–95%) 100%*
  15 years 65% (24–88%) 100%*
  Median (years) 19.8 (2.6–19.8) NR

95% CI: 95% confidence interval; NR: not reached;

*

No failure events were observed