Table 2.
Randomized arm | 55.8 Gy(RBE) | 63.0 Gy(RBE) | p-value |
---|---|---|---|
| |||
Progression-Free Survival (95% CI) | |||
| |||
Entire Cohort | 0.234 | ||
5 years | 91% (68–98%) | 91% (68–98%) | |
10 years | 86% (62–95%) | 81% (58–93%) | |
15 years | 52% (28–72%) | 70% (45–86%) | |
Median (years) | 15.6 (12.3–18.0) | NR | |
| |||
Subtotal Resection | 0.820 | ||
5 years | 100%* | 83% (48–96%) | |
10 years | 91% (51–99%) | 67% (34–86%) | |
15 years | 64% (30–85%) | 57% (25–80%) | |
Median (years) | 16.3 (12.3–18.9) | 16.3 (4.9-NR) | |
| |||
Recurrent | 0.061 | ||
5 years | 82% (45–95%) | 100%* | |
10 years | 82% (45–95%) | 100%* | |
15 years | 39% (7–71%) | 87% (39–98%) | |
Median (years) | 13.5 (2.6-NR) | NR | |
| |||
Overall Survival (95% CI) | |||
| |||
Entire cohort | 0.271 | ||
5 years | 91% (68–98%) | 91% (68–98%) | |
10 years | 86% (62–95%) | 81% (58–93%) | |
15 years | 62% (35–80%) | 75% (50–89%) | |
Median (years) | 16.3 (13.5–18.9) | NR | |
| |||
Subtotal Resection | 0.975 | ||
5 years | 100%* | 83% (48–96%) | |
10 years | 91% (51–99%) | 67% (34–86%) | |
15 years | 64% (30–85%) | 57% (25–80%) | |
Median (years) | 16.3 (12.3–18.9) | 16.3 (4.9-NR) | |
| |||
Recurrent | 0.150 | ||
5 years | 82% (45–95%) | 100%* | |
10 years | 82% (45–95%) | 100%* | |
15 years | 65% (24–88%) | 100%* | |
Median (years) | 19.8 (2.6–19.8) | NR |
95% CI: 95% confidence interval; NR: not reached;
No failure events were observed