Table 1.

Clinical characteristics, imaging traits and pathologic traits assessed in 39 HCCs diagnosed in 38 patients.

Parameter	Classification	Results
Age (y)	Mean ± SD (range)	61 ± 9 (45-82)
Sex	M/F	30/8
Aetiology	HCV/HCV+NASH	36/2
Advanced fibrosis or cirrhosis	Y/N	30/8
Child-Pugh scores	A/B/C	30/6/2
BCLC stage	A/B/C	26/2/10
AJCC stage*	T1/T2/T3/T4	5/19/12/1
Imaging traits (CT/MR imaging: 26/12 patients)
□ T2 hyperintensity**	Yes/No	11/1
□ Fat content**	Yes/No	1/11
□ Single vs. multiple HCCs	Single/multiple	37/2
□ Tumour necrosis	Yes/No	15/24
□ Enhancement characteristics	Wash-in / wash-out	29
	Wash-in / no wash-out	7
	Hypovascular	3
□ Tumour morphology	Nodular/Infiltrative pattern	30/9
□ Macrovascular invasion	Yes/No	8/31
□ Mosaic appearance	Yes/No	30/9
□ Internal arteries	Yes/No	31/8
□ Capsule/pseudocapsule	Yes/No	18/21
□ Extra-nodular growth***	Yes/No	9/9
□ Tumour size (cm)	Mean ± SD (range)	5.7 ± 3.2 (1.5-14.0)
□ Enhancement ratio AP (%)	Mean ± SD	83.88 ± 49.52
□ Enhancement ratio PVP (%)	Mean ± SD	115.25 ± 47.75
□ Wash-out ratio (%)	Mean ± SD	−26.43 ± 32.96
□ Tumour-to-liver contrast ratio AP (%)	Mean ± SD	27.04 ± 35.46
□ Tumour-to-liver contrast ratio PVP (%)	Mean ± SD	−10.42 ± 18.76
Pathologic traits*
□ Tumour size (cm)	Mean ± SD (range)	5.7 ± 3.4 (1.2-15.0)
□ Grade	WD/MD/PD	5/17/16
□ Microvascular invasion	Yes/No	30/8

^*Pathologic information was not available in one patient

^**Assessed in 12 patients with MR imaging

^***Assessed in 18 tumours with capsule/pseudocapsule,

WD = well differentiated, MD= moderately-differentiated, PD= poorly-differentiated, AP = arterial phase, PVP = portal venous phase