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The abundance of key metabolites was measured by GC-MS to examine the impact of lead exposure on the metabolic functions of the gut microbiome. Vitamin E, bile acids and cholesterol and its derivative were significantly reduced in mice after exposure to lead for 13 weeks (A. α-tocopherol, B. γ-tocopherol, C. cholic acid, D. deoxycholic acid, E. ursodeoxycholic acid; F. cholesterol; and G. coprostanol).
