Table 1.

CNSVS cognitive tests and corresponding cognitive domains

Cognitive domain	Test	Score calculation (min–max)b
Memorya	VeMT – immediate word recognition; delayed word recognition; ViMT – immediate figure recognition; delayed figure recognition	VeMT immediate correct hits + correct passes + delayed correct hits + correct passes + ViMT immediate correct hits + correct passes + delayed correct hits + correct passes (0–120)
Processing speed	SDCT – typing in as many correct numbers from 2 to 9 underneath a series of symbols. Each symbol is linked to a number from 2 to 9, presented in a key table that stays visible during the test	SDCT correct responses − SDCT errors
Psychomotor speeda	FTT – pressing the space bar with the right and left index finger as many times in 10 s SDCT – see: Processing speed	FTT right taps average + FTT left taps average + SDCT correct responses
Reaction timea	Stroop test – part 1: Pressing the space bar as soon as the words RED, YELLOW, BLUE, and GREEN appear; Part 2: Pressing the space bar as soon as the color of the word matches the meaning of the word; Part 3: Pressing the space bar as soon as the word does not match the meaning of the word	(Stroop test Part 2 reaction time correct + Part 3 reaction time correct)/2
Executive functioning	SAT – shifting from one instruction set to another quickly and accurately (matching geometric objects either by shape or by color)	SAT correct responses − SAT errors
Cognitive flexibilitya	SAT – see: Executive functioning; Stroop test – see: Reaction time	SAT correct responses − SAT errors − Stroop test Part 3 commission errors
Complex attentiona	CPT – responding to a target stimulus “B”, while not to any other letter; SAT – see: Executive functioning; Stroop test – see: Reaction time	CPT commission errors + CPT omission errors + SAT errors + Stroop test Part 3 commission errors

Notes:

^aThe mean of these domain scores is the NCI;

^bIf applicable.

Abbreviations: CNSVS, central nervous system vital signs; CPT, continuous performance test; FTT, finger tapping test; NCI, neurocognition index; SAT, shifting attention test; SDCT, symbol digit coding test; VeMT, verbal memory test; ViMT, visual memory test.