FIGURE 2.

Expression of HDAC2 in the L4-L5 DRGs of male and female mice after chronic administration with fluoxetine. Chronic administration with fluoxetine (10 mg/Kg, i.p. for 21 days) selectively decreased the expression of HDAC2 in DRGs from female mice (B) but not in male mice (A). (Upper panels) Representative western blot analysis for HDAC2 in DRGs. (Lower panels) Densitometric analysis of HDAC2 bands normalized by actin. Data are the means ± SEM of five animals. ^∗p < 0.05 (Student’s t-test) versus values obtained in animals of the same sex treated with vehicle.