TABLE 3.
Detection of macrolide resistance in the 72 M. genitalium-positive specimensa
| Macrolide resistance assay | No. of specimens yielding Mg DNA/RNA amplification |
Sensitivity (% [no./total of Mg DNA/RNA amplification]) (95% CI) | 23S rRNA mutation |
|||
|---|---|---|---|---|---|---|
| Successful | Unsuccessful | Absent | Present | No. of specimens with accurate macrolide resistance | ||
| 23S rRNA FRET PCR | 38 | 34 | 52.78 (38/72) (41.40–63.87) | 35 | 3 | 3 |
| ResistancePlus MG | 46 | 26 | 63.89 (46/72) (52.35–74.02) | 40 | 6 | 4 |
| RT-PCR and sequencing | 72 | 0 | 100 (72/72) (94.93–100) | 66 | 6 | 6 |
a
Mg, M. genitalium; CI, confidence interval.