TABLE 2.
Number of isolates with mutation/polymorphism(s) in fluoroquinolone resistance-determining genes
| Gene | Mutation/polymorphisma | No. of isolates | Reference |
|---|---|---|---|
| gyrA | T447C (silent) | 2 | |
| T465G (silent) | 1 | ||
| gyrB | G1392A (R464K) | 2 | 14 |
| G1398A (silent) | 1 | ||
| T1485C (silent) | 1 | ||
| parC | A247C (S83R) | 5 | 10 |
| A259A (D87N) | 1 | 10 | |
| G241T (G81C) | 2 | 11 | |
| G248A (S83N) | 1 | 9 | |
| G248T (S83I) | 9 | 10 | |
| C234T (silent) | 36 | ||
| parE | G1297A (A433T) | 1 | |
| C1228T (silent) | 1 | ||
| G1263A (silent) | 2 | ||
| G1384A (silent) | 1 | ||
| G1437A (silent) | 1 | ||
| T1278C (silent) | 3 |
a
The nucleotide numbering shown is based on the M. genitalium position.