FIG 1 .

Breadth and potency are similar as assessed by the percentage of neutralization at the highest tested antibody concentration or IC₅₀. (A) Each square in the heat map represents the average percentage of neutralization for each virus-MAb combination tested: <50%, yellow; 50 to 70%, light orange; 70 to 90%, dark orange; >90%, red. All MAbs were tested at a concentration of 50 µg/ml. Virus subtypes are indicated by color: A, khaki; B, gray; C, turquoise; G, lime green; AC, pink; CRF01_AE, dark green; and CRF07_BC, purple. The branches show the hierarchical clustering with bootstrap probability for 100 iterations. (B) Correlation between BP score estimated from the percentage of neutralization value at 50 µg/ml (y axis) and BP-IC₅₀ (x axis). All IC₅₀s are obtained from the Los Alamos database. (C) Correlation between breadth assessed using either the percentage of neutralization at 50 µg/ml (y axis) or the IC₅₀ (x axis).