Table 1.

Effects of ghrelin on glucose and insulin levels after 2 weeks of administration.

	WT vh	R6/2 vh	R6/2 ghrelin	p-value#	p-value§
Glucose metabolism
Basal glucose (mmol/L)	7.85 ± 0.55	18.21 ± 1.99	17.88 ± 2.03	0.002	>0.9999
Basal Insulin (μg/L)	1.18 ± 0.23	0.40 ± 0.08	0.43 ± 0.07	0.038	>0.9999
HOMA-IR	11.17 ± 2.43	8.68 ± 2.04	7.72 ± 1.47	>0,9999	>0,9999
HOMA-β	147.3 ± 28.41	13.66 ± 2.86	19.47 ± 5.99	<0,0001	>0,9999

The table shows the effects of ghrelin after 2 weeks of treatment. Data are expressed as mean ± SEM. Two-way ANOVA with Bonferroni post hoc test for multiple comparisons was used to analyse data. ^#Represents the p-value between WT and R6/2 treated with vehicle, and ^§represents the p-value between vehicle and ghrelin treatment in R6/2 mice. A p-value below 0.05 was considered significant.