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. 2017 Oct 20;11:507. doi: 10.3389/fnhum.2017.00507

Table 2.

Regions showing significant within group effects in Pain > No-pain image contrasts. Peak MNI effects are displayed for each effect as well as FDR corrected cluster significance values.

Brain Regions Lat MNI Coordinates t-score k P(FDR)
x Y z Cluster
Controls: Pain > No pain
Supplementary motor area L/R 0 3 66 4.89 351 <0.001
Anterior insula L −54 9 −9 4.62 239 <0.001
Inferior frontal gyrus L −57 9 27 4.35
Anterior insula R 57 12 −3 4.38 54 0.045
S/L: Pain > No pain
Cerebellum (VI) R 30 −54 −30 5.48 76 0.011
Primary somatosensory cortex (1/2) L −54 −30 51 5.20 361 <0.001
Secondary somatosensory cortex L −57 −24 21 4.49
Inferior parietal lobule L −50 −33 18 3.92
Dorsal anterior cingulate cortex L/R −3 12 45 5.07 136 0.001
Primary somatosensory cortex (1) R 57 −27 51 4.76 146 0.001
Primary somatosensory cortex (3b) R 54 −18 42 3.79
Anterior insula L −33 12 0 4.51 313 0.001
Parahippocampal gyrus L −21 5 −21 4.47
Anterior insula R 51 3 −3 4.40 105 0.003
Dorsal lateral prefrontal cortex L −30 45 27 4.31 113 0.002
Medial prefrontal cortex L −20 39 39 3.36
Precentral gyrus L −27 0 60 4.27 64 0.017
Caudate nucleus R 15 6 6 3.96 69 0.014
A/G: Pain > No-pain
Supplementary motor area L/R 0 3 66 5.42 780 <0.001
Dorsal anterior cingulate cortex L/R 3 −3 54 4.34
Inferior frontal gyrus (Opercularis) L −57 9 9 4.95 512 <0.001
Temporal pole L −48 12 −9 4.67
Anterior Insula L −45 3 3 4.43
Secondary somatosensory cortex R −60 −21 19 4.81 143 0.027
Ventral striatum R 21 6 −9 4.56 122 0.026
Periaqueductal gray R 12 6 3 4.42
Premotor cortex L 48 −8 56 4.28 137 0.017
Anterior insula R 42 3 3 4.21 100 0.035
Secondary somatosensory cortex L −63 −24 21 4.13 111 0.029