Table 4.

Regions showing significant PPI effects for within group contrasts for at the whole group level and for each pain responder group.

PPI seed	Brain regions	Lat	MNI Coordinates			t-score	K	p(FDR)
			x	y	z
S/L Pain >No-Pain
Left SI/SII	Angular gyrus (IPL – PGp)	L	−39	−75	42	4.77	58	0.050
Right SI/SII	Angular gyrus (IPL – PGa)	L	−36	−75	57	4.31	119	0.002
	Angular gyrus (IPL – PGp)	L	−45	−72	33	3.93
Left AI	Retrosplenial cortex	R	9	−60	42	5.02	62	0.028
Left AI	Temporo-parietal junction	R	36	−51	36	5.18	62	0.028
	Intraparietal sulcus	R	42	−51	45	4.06
Right AI	Temporo-parietal junction	R	42	−54	45	4.36	66	0.024
dACC/SMA	Angular gyrus (IPL - PGp)	L	−39	−75	42	4.48	218	<0.001
dACC/SMA	Middle frontal gyrus	L	−39	21	48	4.52	106	0.001
	Anterior prefrontal cortex	L	−30	9	50	4.25
	DLPFC	L	−48	18	39	4.25
dACC/SMA	DLPFC	R	51	30	21	5.53	55	0.021
A/G Pain > No-pain
Left SI/SII	DMPFC	L	−9	54	15	4.85	78	0.044
	Medial frontopolar cortex	L	−12	51	5	4.14
Left AI	DLPFC	L	−42	48	−3	4.64	91	0.003
S/L (Pain − No-Pain) > Control (Pain − No-Pain)
ACC	DLPFC	R	51	30	21	5.32	44	0.021
Left AI	Temporo-parietal junction	R	42	−51	45	4.89	91	0.003
	Intraparietal sulcus	R	35	−51	35	4.81
Right AI	Temporo-parietal junction	R	42	−51	48	4.65	60	0.034
	Intraparietal sulcus	R	42	−45	39	3.50

Effects are displayed for each seed region's PPI analyses and the direction of the effects are displayed. Only contrasts showing significant effects are displayed.