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. 2017 Oct 20;11:329. doi: 10.3389/fncel.2017.00329

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Copyright © 2017 Wang, Chen and Shan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LV-148b inhibitor reduced brain infarction volume and improved neurological functional recovery after MCAo. (A) Effect of LV-148b inhibitor on infraction volume of rat brains after MCAo; Brain coronal sections stained with H&E show infarction from rats treated with saline, LV-GFP or LV-148b inhibitor after MCAo. (B) Quantitation of infarct volumes in all experimental groups. n = 10/group, mean ± SE, ^*p < 0.05. (C–E) The adhesive-removal test, foot-fault test and mNSS scores test were performed at days1, 4, 7, and 14 after MCAo applied. n = 10/group, mean ± SE, ^*p < 0.05.