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Survival of wild-type M. abscessus ATCC 19977 and ΔMAB_3508c in a 2-fold dilution series of antibiotics in Middlebrook 7H9 medium
| Antibiotic | MIC99 (μg/ml)a |
|
|---|---|---|
| M. abscessus WT (μg/ml) | M. abscessus ΔwhiB7 mutant (μg/ml) | |
| Amikacin | 8 | 2 |
| Clarithromycin | 0.25–0.5 | 0.0625 |
| Erythromycin | 0.5–1 | 0.0625 |
| Spectinomycin | >256 | 32–64 |
| Tetracycline | 16 | 8 |
| Streptomycin | 16 | 8 |
MIC99, the minimum concentration of antibiotic required to inhibit 99% of growth after 96 h.
