FIG 4.

(A and B) Cartoon representations of apo FosA^PA (A) and FosA^KP (B) with dimer interface loops highlighted in yellow. Y65, which bridges the active site and the dimer interface loop, is also marked. (C and D) Apo FosA^PA (C) and FosA^KP (D) color coded by distance (Å) from the center of mass, with active sites marked by yellow arrows. The central dimer interface cavity can be seen in blue. (E) Apo FosA^KP exhibiting close proximity between Y68, which forms the floor of the interface cavity, and H67, which coordinates the active-site metal.