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Neutralization of LukAB-mediated cytotoxicity as a function of the quantity of binding antibody. Samples were adjusted for total IgG per sample (slope of line represents all data; some data points are outside the axis limits). Toxin neutralization by IVIg samples did not correlate with the amount of antibody present (rs = 0.14), unlike that seen with samples from patients with invasive infection (acute-phase rs = 0.64; convalescent-phase rs = 0.83) and from healthy controls (rs = 0.90).
