TABLE 1.

Comparison of activities of BDQ and imipenem against clinical isolates from CF and non-CF patients

Strain	Morphotype	Source	MIC (μg/ml)a
			BDQ	IMP
M. abscessus subsp. abscessus
CIP104536T	S	Non-CF	0.062	16
3321	S	Non-CF	0.062	32
1298	S	CF	0.031	16
2587	S	CF	0.062	16
2069	S	Non-CF	0.062	8
CF	S	CF	0.062	16
2524	R	CF	0.125	32
2648	R	CF	0.062	32
3022	R	Non-CF	0.062	16
5175	R	CF	0.062	32
CIP104536T	R	Non-CF	0.062	16
M. abscessus subsp. massiliense
CIP108297T	R	Addison disease	0.062	32
210	R	CF	0.125	32
179	R	CF	0.062	8
CIP108297T	S	Addison disease	0.062	32
140	S	CF	0.062	32
185	S	CF	0.125	16
107	S	CF	0.125	32
122	S	CF	0.125	16
120	S	CF	0.062	16
212	S	CF	0.125	32
100	S	CF	0.062	16
111	S	CF	0.062	16
M. abscessus subsp. bolletii
CIP108541T	S	Nonreported	0.062	8
114	S	CF	0.125	16
17	S	CF	0.031	32
116	S	CF	0.125	16
97	S	CF	0.125	16
112	R	CF	0.062	16
19	R	Non-CF	0.125	32
10	R	Nonreported	0.062	32
108	R	CF	0.125	32

^aThe MIC was determined in cation-adjusted Mueller-Hinton broth for different subspecies belonging to the M. abscessus complex. BDQ, bedaquiline; IMP, imipenem.