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. 2017 Oct 24;61(11):e01111-17. doi: 10.1128/AAC.01111-17

TABLE 5.

Effects of 24-h daptomycin exposure on isolate susceptibility

Drug tested Incubation with daptomycin MIC50/MIC90 (μg/ml)a
No. susceptible/total no. (%)b No. nonsusceptible/total no. (%)b
MIC50 at 24 h MIC90 at 24 h MIC50 at 48 h MIC90 at 48 h
Daptomycin Preincubation 0.094 0.125 NP NP 48/50 (96) 2/50 (4)
Postincubation >256 >256 NP NP 0/50 (0) 50/50 (100)
Vancomycin Preincubation 0.25 0.38 0.38 0.50 50/50 (100) 0/50 (0)
Postincubation 0.38 0.50 0.50 0.75 50/50 (100) 0/50 (0)
Telavancin Preincubation 0.012 0.016 0.016 0.023 NA NA
Postincubation 0.012 0.016 0.012 0.016 NA NA
a

NP, not performed.

b

Based on CLSI M45, 3rd edition (26). NA, no interpretative data available.