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. 2017 Oct 24;61(11):e01102-17. doi: 10.1128/AAC.01102-17

TABLE 2.

MIC results for 101 consecutive Candida isolates from unique episodes of bloodstream infection

Species and antifungal drug MIC (μg/ml)
Rangea Geometric mean Median Mode MIC50 MIC90
C. albicans (n = 33)
    SCY-078 0.06–0.25 0.08 0.06 0.06 0.06 0.12
    FLC ≤0.125 to 128 1 0.5 0.25 0.5 >128
    ANF ≤0.015 to 1 0.02 ≤0.015 ≤0.015 ≤0.015 0.03
    MCF ≤0.015 to 1 0.02 ≤0.015 ≤0.015 ≤0.015 0.06
    CAS ≤0.015 to 0.5 0.02 ≤0.015 ≤0.015 ≤0.015 0.06
    VRC ≤0.015 to >16 0.08 0.03 ≤0.015 0.03 >16
C. albicans/dubliniensis not further identified (n = 5)
    SCY-078 0.12
    FLC ≤0.125 to 0.25
    ANF ≤0.125 to 0.03
    MCF ≤0.015 to 0.03
    CAS ≤0.015 to 0.03
    VRC ≤0.015
C. glabrata (n = 23)
    SCY-078 0.25–1 0.35 0.25 0.25 0.25 1
    FLC 2 to >128 11 8 8 8 64
    ANF 0.03–1 0.04 0.03 0.03 0.03 0.06
    MCF ≤0.015 to 0.5 0.02 ≤0.015 ≤0.015 ≤0.015 ≤0.015
    CAS ≤0.015 to 0.5 0.02 ≤0.015 ≤0.015 ≤0.015 0.03
    VRC 0.03–8 0.3 0.25 0.25 0.25 1
C. krusei (n = 6)
    SCY-078 0.5–4
    FLC 64–128
    ANF 0.03–0.25
    MCF 0.03–0.25
    CAS 0.06–0.5
    VRC 0.5–1
C. parapsilosis (n = 18)
    SCY-078 0.25–0.5 0.26 0.25 0.25 0.25 0.25
    FLC 0.25–4 0.8 2 1 1 2
    ANF 0.06–2 0.92 1 1 1 2
    MCF 0.5–2 0.98 1 2 1 2
    CAS 0.06–0.5 0.22 0.25 0.25 0.25 0.5
    VRC ≤0.015 to 0.12 0.02 0.03 0.03 0.03 0.06
C. tropicalis (n = 12)
    SCY-078 0.03–0.5 0.1 0.12 0.12 0.12 0.25
    FLC 0.25–1 0.5 0.5 0.5 0.5 1
    ANF ≤0.015 ≤0.015 ≤0.015 ≤0.015 ≤0.015 ≤0.015
    MCF ≤0.015 to 0.06 0.02 ≤0.015 ≤0.015 ≤0.015 0.06
    CAS ≤0.015 to 0.06 0.01 ≤0.015 ≤0.015 ≤0.015 0.03
    VRC ≤0.015 0.03 0.04 0.06 0.03 0.06
C lusitaniae (n = 3)
    SCY-078 1–2
    FLC 0.5–2
    ANF 0.12–0.25
    MCF 0.12
    CAS 0.12–0.25
    VRC ≤0.015
a

Only ranges are reported when the number of isolates tested was less than 10.