FIG 2.
Identification of chondroitin sulfates with inhibitory activity against P. falciparum merozoite invasion. (A) CSD, CSE, and highly sulfated CSB polysaccharides were tested in growth inhibition assays at concentrations of 0 to 100 μg/ml. Data are means ± SEMs from three assays performed in duplicate. (B) Fractionated CSE hexasaccharides were tested in invasion inhibition assays. The degree of sulfation is 5, 6, or 7 sulfate groups per molecule. Data are means ± ranges from one assay performed in duplicate.