TABLE 2.
MICs for various strains in vitro
| Strain | Drug resistancea | MIC (μM) |
||
|---|---|---|---|---|
| NSC 94945 | NSC 4263 | NSC 125531 | ||
| H37Rv | None | 0.61 | 1.25 | 2.5 |
| 210 | None | 0.61 | 1.25 | 5 |
| 31b (RpoBS531T KatGS315T EmbM306V) | INH, Rif, Emb, Kan, SM, Cap | 1.25 | 1.25 | 5 |
| 36b (RpoBH526D KatGS315T EmbM306V) | INH, Rif, Emb | 0.3 | 0.3 | 2.5 |
| 116b (RpoBL511P KatGS315T EmbM306VD354A) | INH, Emb, PAS | 1.25 | 1.25 | 5 |
| 692 | None | 0.61 | 1.25 | 5 |
| 8.1 (MmpL3L567P) | DA8, SQ109 | 0.61 | 1.25 | 2.5 |
| 8.3 (MmpL3D40R) | DA8, SQ109 | 0.61 | 1.25 | 2.5 |
a
INH, isoniazid; Rif, rifampin; Emb, ethambutol; Kan, kanamycin; SM, streptomycin; Cap, capreomycin; PAS, para-aminosalicylic acid.
b
The genotype known from target gene sequencing is shown.