TABLE 3.

MICs for various resistant strains in vitro

Strain	MIC (μM)
	PA-824	NSC 4263	Levofloxacin	INH
NSC 4263-resistant mutant strains
M. bovis BCG (wild type)	0.78	1.56	0.78	0.78
4263 (resistant mutant 1, FbiB−)	>50	12.5	0.78	0.78
4263 (resistant mutant 2, FbiB−)	>50	12.5	0.78	0.78
4263 (resistant mutant 3, FbiB−)	>50	12.5	0.78	0.78
4263 (resistant mutant 4, FbiB−)	>50	12.5	0.78	0.78
4263 (resistant mutant 5, FbiB−)	>50	12.5	0.78	0.78
4263R::pVV16-FbiB 1	1.56	1.56	0.78	0.78
4263R::pVV16-FbiB 2	1.56	1.56	0.78	0.78
PA-824-resistant mutant strains
H37Rv (wild type)	0.78	1.56	0.78	0.78
T3-MT (FGD− F420+)	>50	25	0.78	0.78
50-5A1 (FGD FbiC−)	>50	25	0.78	0.78
50-14A1 (FGD+ Ddn−)	>50	1.56	0.78	0.78
50-7A2 (FGD+ FbiAB−)	>50	25	0.78	0.78
50-14A1-3547 (50-14A1::Rv3547)	0.78	1.56	0.78	0.78