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Amikacin resistance is affected by preincubation with subinhibitory concentrations of various antibiotics in M. abscessus WT and ΔwhiB7 mutant
| Preincubation with ½ the MIC | Amikacin MIC (mg/liter)a |
|
|---|---|---|
| WT | ΔwhiB7 mutant | |
| No drug | 3.1 | 0.8 |
| Clarithromycin | 12.5 | 0.8 |
| Amikacin | 3.1 | 0.8 |
| Chloramphenicol | 6.1 | 0.4 |
| Tigecycline | 12.5 | 0.1 |
Values are the medians of 3 experiments.
