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. 2017 Oct 20;10:332. doi: 10.3389/fnmol.2017.00332

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Copyright © 2017 Desseille, Deforges, Biondi, Houdebine, D’amico, Lamazière, Caradeuc, Bertho, Bruneteau, Weill, Bastin, Djouadi, Salachas, Lopes, Chanoine, Massaad and Charbonnier.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Synthetic summary of energetic metabolism status in fast-twitch tibialis of sedentary and swimming-trained ALS mice at P115. The main experimental alterations observed in the glycolytic and lipidic metabolism (Red arrows) in the fast-twitch tibialis of sedentary ALS (SED ALS) compared to sedentary controls are contrasting with the beneficial effects (blue arrows) of the swimming-based training in ALS mice (SWIM ALS) at 115 days of age. The main metabolites appear in normal typeface while enzymes appear in italic typeface. The colored up arrows correspond to an increase while the down arrows correspond to a decrease.