Table 1.

Demographic and laboratory data for patients with ruptured and non-ruptured HCC undergoing hepatectomy

Variables	Ruptured HCC (n=106)	Non-ruptured HCC (n=201)	P-value
Age (years)	47.9 (22–75)	50.5 (21–78)	0.066
Sex (M:F)	99/7	179/22	0.216
Diabetes	3/103	5/196	0.858
Hypertension	10/96	6/195	0.016*
Liver cirrhosis	89/17	113/88	<0.001*
Child–Pugh (A:B)	96/10	199/2	<0.001*
PT (s)	13.0 (10.4–17.8)	13.3 (9.8–23.5)	0.165
Hemoglobin (g/L)	126 (60–141)	140 (90–155)	<0.001*
TB (µmol/L)	21.8 (6.3–130)	16.1 (5.2–48.3)	<0.001*
Albumin (g/L)	39.7 (23.2–49.4)	40.8 (24.7–55.5)	0.029*
ALT (IU/L)	60.3 (9.1–559.8)	59.4 (9.6–411.4)	0.892
AST (IU/L)	67.9 (12.4–785.1)	59.9 (17.3–353.5)	0.280
Creatinine (µmol/L)	71.9 (39–103)	74.4 (35–242)	0.223
AFP (µg/L)	643.3 (1.5–1000)	771.7 (2–63159)	0.768
AFP >100 µg/L	75/31	113/88	0.013*
Positive HBsAg	98/8	164/37	0.013*
Tumor size (cm)	8.6 (1.8–17.5)	7.1 (1–22)	0.002*
Tumor size >5 cm	89/17	116/85	<0.001*
Tumor location (R/L/both)	72/24/10	145/38/18	0.715
Protrusion	55/51	90/111	0.235
Vascular thrombus	61/45	121/80	0.653
Capsule formation	64/42	130/71	0.459
Satellite lesions	23/83	35/166	0.362
Ascites	51/55	16/185	<0.001*

Notes: Data presented as ratio or mean value (range minimum to maximum).

^*P<0.05.

Abbreviations: AFP, α-fetoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; F, female; HBsAg, hepatitis B surface antigen; HCC, hepatocellular carcinoma; L, left; M, male; PT, prothrombin time; R, right; TB, total bilirubin.