Table 4.

Cox proportional hazards analyses of OS in 307 patients with HCC

Variables	SE	Wald	Exp(B)	95% CI	P-value
Maximum tumor size (≥5 vs <5 cm)	0.183	9.047	1.736	1.212–2.486	0.003
AFP (≥400 vs <400 µg/L)	0.153	9.251	1.591	1.179–2.145	0.002
Tumor type (unifocal vs multiple/diffuse)	0.169	9.704	1.692	1.215–2.355	0.002
Microscopic vascular invasion (yes vs no)	0.208	16.134	2.302	1.533–3.459	<0.001
Child–Pugh grade (A vs B)	0.417	4.068	0.431	0.190–0.977	0.044
STR (yes vs no)	0.181	12.328	1.889	1.324–2.694	<0.001

Abbreviations: AFP, α-fetoprotein; CI, confidence interval; HCC, hepatocellular carcinoma; OS, overall survival; SE, standard error; STR, spontaneous tumor rupture.