Table 1.
Patient characteristics and perioperative data
Characteristics | All patients (N=15) |
---|---|
Age (years), mean (range) | 52.4 (36–74) |
Gender, male: female | 9:6 |
Neoadjuvant chemotherapy, n (%) | 9 (60) |
Pre-CRS L-HIPEC, n (%) | 4 (26.7) |
NIPS, n (%) | 1 (6.7) |
PSS, n (%) | |
0 | 2 (13.3) |
1 | 9 (60.0) |
2 | 4 (26.7) |
CEA (ng/mL), (normal 0–5 ng/mL), mean (range) | 21.2 (0.9–145.0) |
CA19–9 (U/mL), (normal 0–37 U/mL), mean (range) | 23.3 (1.0–127.0) |
CA125 (U/mL), (normal 0–35 U/mL), mean (range) | 70.8 (6.2–181.3) |
Ascites, n (%) | 10 (66.7) |
PCI, mean ± SD (range), median | |
Preoperative | 23.1±12.9 (0–39), 26 |
Postoperative | 16.6±14.2 (0–39), 18 |
CC, n (%) | |
0 | 3 (20.0) |
1 | 1 (6.7) |
2 | 5 (33.3) |
3 | 6 (40.0) |
HIPEC regimen, n (%) | |
Nil | 4 (26.7) |
MMC | 8 (53.3) |
5-FU + oxaliplatin | 3 (20.0) |
Colostomy or ileostomy, n (%) | 5 (33.3) |
EPIC, n (%) | 6 (40) |
Operation time (minutes), mean (range) | 230 (170–375) |
Blood loss (mL), mean (range) | 1098 (200–3000) |
Morbidity, n (%) | |
Grade 0 | 8 (53.3) |
Grade 1–2 | 5 (33.3) |
Grade 3–5 | 2 (13.4) |
Admission days, median ± SD (range) | 28±53.0 (12–190) |
Adjuvant chemotherapy, n (%) | 6 (40) |
Abbreviations: 5-FU, 5-fluorouracil; CC, completeness of cytoreduction; CEA, carcinoembryonic antigen; CRS, cytoreductive surgery; EPIC, early postoperative intraperitoneal chemotherapy; GCCs, goblet cell carcinomas; HIPEC, hyperthermic intraperitoneal chemotherapy; L-HIPEC, laparoscopic HIPEC; MMC, mitomycin C; NIPS, neoadjuvant intraperitoneal and systemic chemotherapy; PCI, peritoneal cancer index; PSS, prior surgical score.