Figure 3. WT161 downregulates EGFR and ERα expression.
A. MCF7 cells were cultured with WT161 (1 μM) for 0 - 48h. B. MCF7 and T47D cells were cultured with WT161 (0 - 1 μM) for 48h. Whole cell lysates were subjected to immunoblotting with indicated Abs. C. MCF7 cells were cultured with WT161 (0 - 2 μM) for 24h. Total RNAs were extracted and subjected to PCR.