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. 2017 Sep 8;8(46):80175–80181. doi: 10.18632/oncotarget.20706

Table 2. Age-, sex-adjusted mean of kidney function tests level across quartiles of telomere length.

Variables Quarters of telomere length P-
Q1 Q2 Q3 Q4 trend†
TL, Mean ±SEM (T/S ratio) 0.73±0.02 0.92±0.01 1.08±0.01 1.38±0.06
Body Mass Index (kg/m2) 28.5± 0.18 28.1±0.19 27.8±0.42 26.4±0.21 <0.001
Fat-free mass (kg) 54.8±0.94 54.4±0.96 53.4±0.74 51.0±0.68 <0.001
Fat mass (kg) 26.9± 0.89 25.8±0.32 24.9±0.76 24.1±0.96 <0.001
Triglyceride (mg/dl) 150.7± 5.7 142.1±6.2 140.1±5.9 133.0±5.1 <0.001
Low density lipoprotein cholesterol(mg/dl) 123.0±1.95 124.1±1.49 122.0±1.29 124.1±1.46 0.615
Total cholesterol(mg/dl) 203.1±1.9 199.6±1.07 189.3±1.92 180.7±1.46 <0.001
High density lipoprotein cholesterol(mg/dl) 49.3±0.62 51.1±0.49 52.1±0.73 54.0±0.82 <0.001
Systolic blood pressure 122.0±0.68 121.3±0.66 122.5±0.39 122.8±0.54 0.169
Diastolic blood pressure 72.06 ±0.54 73.2± 0.40 73.8±0.62 72.4±0.31 0.069
Fasting blood glucose(mg/dl) 101.0±1.2 101.3±1.05 102.4±1.82 101.9±2.31 0.905
C-reactive protein(mg/dL) 0.53±0.02 0.46±0.01 0.40±0.01 0.32±0.03 <0.001
Log Cystatin C (mg/L) 0.90±0.01 0.083±0.01 0.80±0.02 0.74±0.02 <0.001
Urea Albumin (ug/mL) 44.9±5.36 39.5±8.68 32.8±7.36 27.4± 4.43 <0.001
Glomerular filtration rate (mL/min) 96.5±0.92 99.9±0.74 101.4±0.64 106.2±0.69 <0.001
Log Albumin-Creatinine Ratio (mg/dl) 3.16±0.03 2.96±0.03 2.43±0.03 1.95±0.02 <0.001

a P-values for linear trend across quarters of telomere length. Variables were compared across quartiles of telomere length using analysis of variance (ANOVA) test .CKD: chronic kidney disease.