Table 2. Age-, sex-adjusted mean of kidney function tests level across quartiles of telomere length.
Variables | Quarters of telomere length | P- | |||
Q1 | Q2 | Q3 | Q4 | trend† | |
TL, Mean ±SEM (T/S ratio) | 0.73±0.02 | 0.92±0.01 | 1.08±0.01 | 1.38±0.06 | |
Body Mass Index (kg/m2) | 28.5± 0.18 | 28.1±0.19 | 27.8±0.42 | 26.4±0.21 | <0.001 |
Fat-free mass (kg) | 54.8±0.94 | 54.4±0.96 | 53.4±0.74 | 51.0±0.68 | <0.001 |
Fat mass (kg) | 26.9± 0.89 | 25.8±0.32 | 24.9±0.76 | 24.1±0.96 | <0.001 |
Triglyceride (mg/dl) | 150.7± 5.7 | 142.1±6.2 | 140.1±5.9 | 133.0±5.1 | <0.001 |
Low density lipoprotein cholesterol(mg/dl) | 123.0±1.95 | 124.1±1.49 | 122.0±1.29 | 124.1±1.46 | 0.615 |
Total cholesterol(mg/dl) | 203.1±1.9 | 199.6±1.07 | 189.3±1.92 | 180.7±1.46 | <0.001 |
High density lipoprotein cholesterol(mg/dl) | 49.3±0.62 | 51.1±0.49 | 52.1±0.73 | 54.0±0.82 | <0.001 |
Systolic blood pressure | 122.0±0.68 | 121.3±0.66 | 122.5±0.39 | 122.8±0.54 | 0.169 |
Diastolic blood pressure | 72.06 ±0.54 | 73.2± 0.40 | 73.8±0.62 | 72.4±0.31 | 0.069 |
Fasting blood glucose(mg/dl) | 101.0±1.2 | 101.3±1.05 | 102.4±1.82 | 101.9±2.31 | 0.905 |
C-reactive protein(mg/dL) | 0.53±0.02 | 0.46±0.01 | 0.40±0.01 | 0.32±0.03 | <0.001 |
Log Cystatin C (mg/L) | 0.90±0.01 | 0.083±0.01 | 0.80±0.02 | 0.74±0.02 | <0.001 |
Urea Albumin (ug/mL) | 44.9±5.36 | 39.5±8.68 | 32.8±7.36 | 27.4± 4.43 | <0.001 |
Glomerular filtration rate (mL/min) | 96.5±0.92 | 99.9±0.74 | 101.4±0.64 | 106.2±0.69 | <0.001 |
Log Albumin-Creatinine Ratio (mg/dl) | 3.16±0.03 | 2.96±0.03 | 2.43±0.03 | 1.95±0.02 | <0.001 |
a P-values for linear trend across quarters of telomere length. Variables were compared across quartiles of telomere length using analysis of variance (ANOVA) test .CKD: chronic kidney disease.