Table 3. Univariate and multivariate analysis of the correlation between clinicopathological parameters and prognostic significance of GC patients.
| Variables | Univariate analysis | P value | Multivariate analysis | P value |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Sex(male vs. female) | 1.847 (0.926–3.684) | 0.082 | ||
| Age* (> 57.5 vs. < 57.5) | 1.495 (0.862–2.594) | 0.152 | ||
| Depth of invasion (T1/T2 vs. T3/T4) | 0.122 (0.044–0.338) | 0.000 | 0.221 (0.066–0.737) | 0.014 |
| LNM (Yes vs. No) | 7.203 (3.066–16.923) | 0.000 | 3.717 (0.862–16.027) | 0.078 |
| Tumor size (< 6 cm vs. > = 6 cm) | 0.391 (0.208–0.734) | 0.003 | 0.390 (0.190–0.802) | 0.010 |
| Differentiation(Low/undifferentiate vs. High/moderate) | 0.784 (0.439–1.401) | 0.412 | ||
| TNM stage (I/II vs. III) | 0.158 (0.077–0.325) | 0.000 | 0.863 (0.224–3.320) | 0.830 |
| HSPC111 (positive vs. negative) | 1.925 (1.116–3.319) | 0.019 | 2.532 (0.843–7.603) | 0.098 |
| Nuclear YAP1 (positive vs. negative) | 3.458 (1.912–6.252) | 0.000 | 5.113 (2.123–12.316) | 0.000 |
| HSPC111/Nuclear YAP1 (HSPC111+/Nuclear YAP1+ vs. all others) | 3.128 (1.784–5.483) | 0.000 | 0.483 (0.130–1.792) | 0.277 |
Age* = mean age; LNM = lymph node metastasis.