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. 2017 May 22;8(46):80336–80347. doi: 10.18632/oncotarget.18165

Table 2. Univariate Cox regression analysis of overall survival in each cohort.

Clinical features Number P HR 95%CIs of HR
Risk score (High-risk/Low-risk) 129/129 < 0.001 1.445 1.321 1.581
Gender(male/female) 118/140 0.439 1.172 0.784 1.751
Age(< = 60/> 60) 128/130 0.134 1.357 0.91 2.023
Leiomyosarcoma histologic subtype(poorly differentiated or pleomorphic or epithelioid leiomyosarcoma/conventional leiomyosarcoma/well-differentiated leiomyosarcoma (resembling leiomyoma) 34/64/4 0.025 0.592 0.303 0.924
leiomyosarcoma major vessel involvement(yes/no) 12/78 0.483 0.685 0.239 1.968
New neoplasm event type(new primary tumor /distant metastasis/locoregional recurrence) 5/41/29 0.668 0.885 0.506 1.548
Local disease recurrence(yes/no) 29/143 0.002 2.316 1.37 3.916
Metastatic diagnosis(yes/no) 56/119 < 0.001 3.009 1.831 4.946
Tumor depth(deep/superficial) 184/21 0.069 2.924 0.921 9.285
Contiguous organ invaded(yes/no) 14/43 0.012 2.809 1.261 6.261
Margin status(positive/negative) 73/136 0.013 1.84 1.138 2.974
Person neoplasm cancer status(with tumor/tumor free) 124/124 < 0.001 9.532 5.07 17.92
Residual tumor(yes/no) 154/78 < 0.001 2.553 1.668 3.909
Tumor total necrosis percent(0/< 10%/> = 10%,< 50% 12/61/38 0.121 1.207 0.952 1.532
Radiation therapy(yes/no) 73/179 0.508 0.882 0.566 1.376
Treatment completion success outcome(SD/PD/CR/PR) 124/3/8/64 < 0.001 2.386 1.795 3.171