Table 1. Baseline characteristics of the patients with OSCC and distribution of KDM4A by selected study variables.
| Variable | No. of Patients No. (%) | KDM4A | P Value# | ||
|---|---|---|---|---|---|
| Low expression No. (%) | High expression No. (%) | ||||
| Sex | Male | 213 (68.05) | 99 (46.48) | 114 (53.52) | 0.477 |
| Female | 100 (31.95) | 53 (53.00) | 47 (47.00) | ||
| Age | > 60 yr | 154 (49.20) | 84 (52.60) | 73 (47.4) | 0.260 |
| ≤ 60 yr | 159 (50.80) | 71 (44.65) | 88 (55.35) | ||
| Smoking history | Never | 167 (53.35) | 80 (47.90) | 87 (52.10) | 0.903 |
| Ever | 146 (46.65) | 72 (49.32) | 74 (50.68) | ||
| Drinking history | Never | 182 (58.15) | 90 (49.45) | 92 (50.55) | 0.732 |
| Ever | 131 (41.85) | 62 (47.33) | 69 (52.67) | ||
| Location | Buccal mucosa | 52 (16.61) | 27 (51.92) | 25 (48.08) | 0.991 |
| Tongue | 114 (36.42) | 54 (47.37) | 60 (52.63) | ||
| Gingiva | 66 (21.09) | 34 (51.52) | 32 (48.48) | ||
| Others* | 81 (25.88) | 37 (45.68) | 44 (54.32) | ||
| Cell differentiation | High | 193 (61.34) | 96 (49.48) | 97 (50.52) | 0.951 |
| Moderate | 92 (29.39) | 42 (45.65) | 50 (54.35) | ||
| Low | 28 (8.95) | 14 (50.00) | 14 (50.00) | ||
| Tumor stage | T1 | 45 (14.38) | 21 (46.67) | 24 (53.33) | 0.101 |
| T2 | 139 (44.41) | 71 (51.08) | 68 (48.92) | ||
| T3 | 61 (19.49) | 35 (57.38) | 26 (42.62) | ||
| T4 | 68 (21.73) | 25 (36.76) | 43 (63.24) | ||
| Lymph node metastasis | No | 168 (53.67) | 94 (55.95) | 74 (44.05) | 0.017 |
| Yes | 145 (46.33) | 68 (40.00) | 87 (60.00) | ||
| TNM stage | I | 37 (11.82) | 23 (62.16) | 14 (37.84) | 0.011 |
| II | 94 (30.03) | 55 (58.51) | 39 (41.49) | ||
| III | 127 (40.58) | 55 (43.31) | 72 (56.69) | ||
| IV | 55 (17.57) | 19 (34.55) | 36 (65.45) | ||
Abbreviations: P Value# was determined using the Kruskal-Wallis and chi-square tests.
Others* included floor of mouth, lips and palate.