Table 4. Somatic variations of KMT2C in osteosarcoma samples and their genomic and amino acid change.
| Sample | Genomic change | Aminoacid |
|---|---|---|
| 1 | c.2963G>T | p.Cys988Phe |
| 1 | c.8326G>A | p.Glu2776Lys |
| 1 | c.11927C>A | p.Pro3976Gln |
| 1 | c.12014C>T | p.Ser4005Phe |
| 1 | c.14521G>A | p.Gly4841Arg |
| 2 | c.1277C>A | p.Pro426Gln |
| 2 | c.6632G>C | p.Arg2211Thr |
| 2 | c.5459C>G | p.Ser1820Cys |
| 2 | c.8174A>G | p.Glu2725Gly |
| 2 | c.9622T>C | p.Ser3208Pro |
| 2 | c.9617G>C | p.Arg3206Thr |
| 4 | c.10383T>G | p.Asp3461Glu |
| 5 | c.404C>T | p.Ala135Val |
| 5 | c.3155A>T | p.Lys1052Ile |
| 5 | c.3119C>A | p.Pro1040Gln |
| 5 | c.3029G>T | p.Cys1010Phe |
| 5 | c.5669G>C | p.Arg1890Pro |
| 5 | c.7318C>T | p.Pro2440Ser |
| 5 | c.7214A>G | p.Glu2405Gly |
| 5 | c.9182A>G | p.Gln3061Arg |
| 5 | c.9769G>A | p.Glu3257Lys |
| 6 | c.925C>T | p.Pro309Ser |
| 6 | c.1181G>A | p.Cys394Tyr |
| 6 | c.2512G>A | p.Gly838Ser |
| 6 | c.2468T>C | p.Ile823Thr |
| 6 | c.2459C>T | p.Thr820Ile |
| 6 | c.2656C>T | p.Arg886Cys |
| 7 | c.943G>A | p.Gly315Ser |
| 7 | c.925C>T | p.Pro309Ser |
| 7 | c.2512G>A | p.Gly838Ser |
| 7 | c.2468T>C | p.Ile823Thr |
| 7 | c.2963G>T | p.Cys988Phe |
| 7 | c.2917A>G | p.Arg973Gly |
| 8 | c.943G>A | p.Gly315Ser |
| 8 | c.2512G>A | p.Gly838Ser |
| 8 | c.2468T>C | p.Ile823Thr |