Table 4. Relation of SNPs to type 2 DM as determined by multivariable logistic regression analysis.
| Gene | SNP | Dominant | Recessive | Additive 1 | Additive 2 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | |||
| RUFY1 | rs138313632 | T/G (S705A) | 4.20 × 10−8 | 0.20 (0.09–0.39) | ND | 4.20 × 10−8 | 0.20 (0.09–0.39) | ND | ||
| C21orf59 | rs76974938 | C/T (D67N) | 1.00 × 10−23 | 0.33 (0.26–0.41) | ND | 1.00 × 10−23 | 0.33 (0.26–0.41) | ND | ||
| LOC100505549 | rs139012426 | G/C (S1242T) | 2.28 × 10−6 | 0.22 (0.09–0.44) | ND | 2.28 × 10−6 | 0.22 (0.09–0.44) | ND | ||
| TRABD2B | rs147317864 | C/T (A262T) | 2.25 × 10−5 | 1.21 × 108 (ND) | ND | 2.25 × 10−5 | 1.21 × 108 (ND) | ND | ||
Multivariable logistic regression analysis was performed with adjustment for age and sex. Based on Bonferroni's correction, P values of <1.44 × 10−4 (0.05/348) were considered statistically significant and are shown in bold. OR, odds ratio; CI, confidence interval; ND, not determined.