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. 2017 Jul 26;8(46):80568–80588. doi: 10.18632/oncotarget.19631

Figure 8. NO induces increased TNFα secretion and activation of NF-κB in HCC1806.

Figure 8

TNFα released (A) in the three cell lines after 24 hours exposure to vehicle or 0.5mM of DETA/NO alone or in combination with 100nM of PD153035. (B) Luciferase activity of NF-κB reporter after 24 hours exposure to vehicle or 0.5mM of DETA/NO alone or in combination with 50μg/ml of Infliximab (TNFα blocking antibody), 10ng/ml of recombinant TNFα were used as a positive control. * p<0.05 vs vehicle; # p<0.05 vs DETA/NO plus PD153035.