Table 3. The relationships between genetic polymorphism and telomere lengths.
| SNPs | Exposure | Control | ||||||
|---|---|---|---|---|---|---|---|---|
| n | M (P25, P75) | Z | P** | n | M (P25, P75) | Z | P** | |
| GSTT1 | ||||||||
| + | 99 | 1.50 (1.06,2.69) | 0.653 | 0.514 | 67 | 0.94 (0.74,1.27) | 1.100 | 0.271 |
| − | 81 | 1.50 (1.19,2.43) | 48 | 1.04 (0.77,1.45) | ||||
| GSTM1 | ||||||||
| + | 85 | 1.42 (1.07,2.14) | 1.266 | 0.205 | 51 | 0.91 (0.71,1.08) | 2.911 | 0.004 |
| − | 95 | 1.60 (1.16,2.91) | 64 | 1.12 (0.77,1.47) | ||||
| GSTP1 rs1695 | ||||||||
| GG+AG | 54 | 1.73 (1.30,3.16) | 2.262 | 0.024 | 44 | 0.94 (0.78,1.34) | 0.253 | 0.800 |
| AA | 126 | 1.46 (1.06,2.24) | 71 | 0.94 (0.75,1.32) | ||||
| CYP2E1rs6413432 | ||||||||
| TT | 97 | 1.50 (1.15,2.37) | Ref* | 68 | 0.94 (0.74,1.33) | Ref* | ||
| AT | 72 | 1.50 (1.02,2.97) | 0.286 | 0.775 | 42 | 1.04 (0.79,1.29) | 0.381 | 0.704 |
| AA | 11 | 1.64 (1.05,3.17) | 0.276 | 0.782 | 5 | 0.71 (0.65,1.21) | 1.157 | 0.247 |
| χ2 (P*) | 0.200 (0.905) | 1.668 (0.434) | ||||||
| CYP2E1rs3813867 | ||||||||
| GG | 106 | 1.50 (1.13,2.46) | Ref* | 60 | 0.95 (0.73,1.35) | Ref* | ||
| CG | 65 | 1.50 (1.03,2.70) | 0.395 | 0.693 | 50 | 1.04 (0.79,1.30) | 0.381 | 0.703 |
| CC | 9 | 1.64 (1.11,4.16) | 0.698 | 0.485 | 5 | 0.71 (0.65,1.00) | 1.613 | 0.107 |
| χ2 (P*) | 0.760 (0.684) | 3.083 (0.214) | ||||||
| PON2 rs12026 | ||||||||
| CC | 125 | 1.48 (1.08,2.53) | 1.099 | 0.272 | 62 | 0.94 (0.74,1.34) | 0.443 | 0.658 |
| CG+GG | 55 | 1.66 (1.20,2.74) | 53 | 0.95 (0.76,1.32) | ||||
P*: To compare telomere lengths among genotypes using a rank test of k independent samples; P**: The comparing results between the two groups, the Bonferroni method was adopted; * Ref: The reference group of comparing different genotypes.