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. 2017 Sep 19;8(46):80688–80699. doi: 10.18632/oncotarget.21079

Table 3. Subject characteristics at the end of study.

Total Male sex Female sex
Normouricemia Hyperuricemia p-value Normouricemia Hyperuricemia p-value Normouricemia Hyperuricemia p-value
Age, years 73.7 ± 6.1 73.5 ± 5.8 0.637 73.9 ± 6.1 73.6 ± 5.9 0.256 73.5 ± 6.0 73.2 ± 5.8 0.209
BMI, kg/m2 22.1 ± 1.5 22.2 ± 1.6 0.324 22.3 ± 1.5 22.6 ± 1.6 0.431 22.0 ± 1.5 22.1 ± 1.5 0.143
Systolic BP, mmHg 122.4 ± 11.1 123.7 ± 9.8 0.029 122.7 ± 11.0 123.8 ± 9.1 0.137 122.1 ± 10.7 122.9 ± 10.3 0.168
Diastolic BP, mmHg 75.8 ± 7.4 75.7 ± 7.3 0.631 75.9 ± 7.5 76.0 ± 7.4 0.346 75.1 ± 7.5 75.6 ± 7.2 0.516
Pulse rate, bpm 74.5 ± 10.2 74.8 ± 9.8 0.241 74.8 ± 10.8 75.0 ± 9.7 0.673 74.5 ± 10.0 74.3 ± 10.4 0.238
Current smoking 27.7% 60.3% < 0.001 55.9% 61.8% < 0.001 14.3% 26.1% < 0.001
Drinking habits 36.9% 68.6% < 0.001 60.9% 70.7% < 0.001 15.2% 28.7% < 0.001
Hemoglobin (g/dL) 12.9 ± 1.2 13.8 ± 1.1 < 0.001 13.1 ± 1.2 13.9 ± 1.2 < 0.001 12.7 ± 1.1 13.6 ± 1.2 < 0.001
Total protein, g/dL 7.1 ± 0.5 7.3 ± 0.5 < 0.001 7.2 ± 0.5 7.4 ± 0.6 < 0.001 7.0 ± 0.5 7.2 ± 0.6 < 0.001
Albumin, g/dL 4.2 ± 0.4 4.3 ± 0.4 < 0.001 4.2 ± 0.4 4.3 ± 0.4 0.092 4.2 ± 0.4 4.3 ± 0.4 < 0.001
Serum creatinine, mg/dL 0.9 ± 0.1 1.0 ± 0.1 < 0.001 0.9 ± 0.1 1.0 ± 0.1 < 0.001 0.8 ± 0.1 0.9 ± 0.1 < 0.001
eGFR, ml/min per 1.73m2 81.1 ± 12.3 76.4 ± 11.9 < 0.001 82.3 ± 11.7 79.3 ± 11.8 < 0.001 78.5 ± 11.7 75.3 ± 11.2 < 0.001
SUA, mg/dL 5.3 ± 1.5 9.1 ± 1.7 < 0.001 5.4 ± 1.2 9.2 ± 1.8 < 0.001 5.2 ± 1.1 8.8 ± 1.7 < 0.001
Triglycerides(mmol/L) 1.7 ± 1.0 2.0 ± 1.0 < 0.001 1.8 ± 0.9 2.1 ± 1.0 < 0.001 1.6 ± 0.9 1.9 ± 1.1 < 0.001
Total-cholesterol(mmol/L) 5.3 ± 1.2 5.4 ± 1.2 < 0.001 5.4 ± 1.2 5.5 ± 1.2 0.010 5.2 ± 1.0 5.3 ± 1.2 < 0.001
LDL(mmol/L) 3.4 ± 1.0 3.6 ± 1.0 < 0.001 3.4 ± 1.0 3.6 ± 0.9 < 0.001 3.4 ± 0.9 3.5 ± 1.0 < 0.001
HDL(mmol/L) 1.6 ± 0.6 1.4 ± 0.5 < 0.001 1.5 ± 0.5 1.3 ± 0.5 < 0.001 1.7 ± 0.5 1.5 ± 0.5 < 0.001

BMI = body mass index; BP = blood pressure; eGFR = estimated glomerular filtration rate; SUA = serum uric acid; LDL = low density lipoprotein; HDL = high density lipoprotein.