Table 4. Baseline serum uric acid and hyperuricemia as a risk for incident CAD events in the subjects.

	Crude			Model 1			Model 2			Model 3
	HR	95% CI	p-value	HR	95% CI	p-value	HR	95% CI	p-value	HR	95% CI	p-value
Total = 2142
Hyperuricemia	1.82	1.36–2.46	< 0.001	1.85	1.38–2.50	< 0.001	1.84	1.37–2.50	< 0.001	1.71	1.26–2.34	0.001
Per SUA 1mg/dL	1.18	1.11–1.25	< 0.001	1.17	1.10–1.24	< 0.001	1.15	1.10–1.25	0.001	1.12	1.04–1.21	0.001
Male sex = 1194
Hyperuricemia	1.78	1.21–2.62	0.003	1.84	1.25–2.70	0.002	1.83	1.24–2.70	0.023	1.79	1.26–2.78	0.024
Per SUA 1mg/dL	1.18	1.10–1.27	< 0.001	1.15	1.08–1.29	< 0.001	1.10	1.05–1.31	< 0.001	1.07	1.02–1.20	0.046
Female sex = 948
Hyperuricemia	1.87	1.16–3.02	0.011	1.85	1.37–2.50	< 0.001	1.84	1.36–2.49	< 0.001	1.41	1.10–1.98	0.009
Per SUA 1mg/dL	1.16	1.10–1.29	< 0.001	1.15	1.08–1.38	< 0.001	1.13	1.07–1.39	0.001	1.11	1.06–1.40	0.003

SUA indicated baseline serum uric acid level.

Model 1: Data adjusted for baseline age, sex, smoking and drinking habits.

Model 2: Data adjusted for baseline age, sex, smoking and drinking habits, baseline BMI, baseline systolic BP and diastolic BP.

Model 3: Data adjusted for baseline age, sex, smoking and drinking habits, baseline BMI, baseline systolic BP and diastolic BP, and baseline eGFR, total-cholesterol, triglycerides, LDL and HDL.

CAD = coronary artery disease; BMI = body mass index; BP = blood pressure; eGFR=estimated glomerular filtration rate; SUA = serum uric acid; LDL = low density lipoprotein; HDL= high density lipoprotein; HR = hazards ratio; C I= confidence interval.