Skip to main content
. 2017 Aug 18;8(46):80757–80769. doi: 10.18632/oncotarget.20358

Figure 8. Effects of miR-132 on the radiosensitivity of Hela cell-induced tumors in nude mice.

Figure 8

(A) Growth curve for transplanted tumors. After treatment with miRNA Agomir beginning on the 22nd day, tumor growth was slower in the miR-132-agomir + 8 Gy and siBmi-1 + 8Gy groups than in the NC-agomir + 8 Gy group; this difference increased as treatment continued. (B and C) On the 35th day after tumor transplantation, mice were sacrificed and tumors were removed, weighed, and photographed. Tumor weights were higher in the NC-agomir + 8 Gy group than in the miR-132-agomir + 8Gy and siBmi-1 + 8 Gy groups. (D) qRT-PCR performed using a small amount of transplanted tissue revealed that miR-132 expression in the miR-132-agomir + 8 Gy group was elevated compared to the NC-agomir + 8 Gy group. *P < 0.05 compared to the NC-agomir + 4 Gy group.