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. 2017 Sep 8;8(46):80878–80888. doi: 10.18632/oncotarget.20718

Figure 2. Downregulation of B7-H4 suppresses cell growth and apoptosis in HCC cells.

Figure 2

(A-B) The knockdown effects of B7-H4 in SMMC7721 and HepG2 cells by B7-H4 via RT-qPCR and western blot. (C) The relative cell viability of SMMC7721 and HepG2 cells at 24-72 h after B7-H4 downregulation. (D) The representative images showed that the increase apoptotic cells were observed by flow cytometry analysis in both SMMC7721 and HepG2 cells with siB7-H4 transfection. (E) B7-H4 RNAi influenced the expression of molecules associated with apoptosis via JUK activation. Data was presented as mean ± SD; *p<0.05.