Table 6. The association of CCND1 rs1944129 polymorphism and clinicopathologic characteristics of ccRCC patients.
| Variables | Risk allele | P* | Adjusted OR (95% CI)* | |||
|---|---|---|---|---|---|---|
| AA | AG+GG | |||||
| N | % | N | % | |||
| Clinical stage | 824 | 664 | ||||
| I | 520 | 63.1 | 426 | 64.2 | 1.00 (reference) | |
| II | 168 | 20.4 | 135 | 20.3 | 0.113 | 0.77 (0.56-1.06) |
| III | 59 | 7.2 | 56 | 8.4 | 0.611 | 0.89 (0.56-1.40) |
| IV | 77 | 9.3 | 47 | 7.1 | 0.029 | 0.56 (0.33-0.94) |
| Grade | ||||||
| I | 175 | 21.20 | 144 | 21.7 | 1.00 (reference) | |
| II | 409 | 49.60 | 335 | 50.5 | 0.639 | 0.96 (0.81-1.14) |
| III | 178 | 21.60 | 144 | 21.7 | 0.670 | 0.92 (0.62-1.36) |
| IV | 62 | 7.50 | 41 | 6.2 | 0.818 | 0.91 (0.42-1.99) |
* Two-sided χ2 test for number of alleles in cases and controls; 95% CI: 95% confidence interval. Adjusted for age, BMI, gender, smoking status, drinking status and history of hypertension and diabetes in logistic regression model.