Table 2. GM reductions in patients with PSP compared to healthy controls.
| Cluster | Anatomical label | Peak MNI coordinate (x, y, z) | No. of voxels | SDM-Z value | SDM-p value | Egger's test (p value) |
|---|---|---|---|---|---|---|
| A | Left inferior frontal gyrus/insula/superior temporal gyrus/precentral gyrus (premotor cortex)/putamen/OFC (BAs 47, 13, 44, 22, 6, 45, and 9) | -48, 18, 0 | 5063 | -4.80 | ∼0 | 0.56 |
| B | Right/Left thalamus/midbrain/caudate nucleus | 4, -14, 6 | 3916 | -4.70 | ∼0 | 0.29 |
| C | Right/Left ACC/(pre-) SMA/superior medial frontal cortex/medial OFC (BAs 32, 24, 8, 9, 6,11, and 10) | -4, 12, 44 | 3457 | -3.32 | 0.000067 | 0.27 |
| D | Right inferior frontal gyrus/insula/superior temporal gyrus/putamen/precentral gyrus (premotor cortex) (BAs 44, 13, 47, 22, 6, 45, and 9) | 54, 16, 16 | 3186 | -4.27 | 0.027743R254 | 0.78 |
| E | Left anterior cerebellum (lobule III/IV/V) | -14, -44, -24 | 108 | -2.74 | 0.0014 | 0.83 |
Key: GM, Gray Matter; PSP, Progressive Supranuclear Palsy; MNI, Montreal Neurological Institute; No., Number; SDM, Seed-based d Mapping; BA, Brodmann Area; OFC, Orbitofrontal Cortex; ACC, Anterior Cingulate Cortex; SMA, Supplementary Motor Area.