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. 2017 Sep 15;8(46):80956–80970. doi: 10.18632/oncotarget.20898

Figure 3. CHERP depletion induces cell cycle arrest in vitro.

Figure 3

CHERP depletion significantly increased the proportion of the cell population at G1 phase and decreased the proportion of cells in S phase in neuroblastoma. (A) Cell cycle analysis of BE(2)-C and SHEP1 cells using flow cytometry. (B) Ki67 staining analysis with Ki67 (red) and DAPI (blue). Quantification of Ki67-positive cells is presented on the right; all data were measured at least three times and were obtained from three independent images. Values are shown as the mean ± SD, **p < 0.001. (C) Expression of cyclins and CDKs associated with G1 phase as detected using western blotting.