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The AD mice were treated with NP control, NP-S1, NP-Cur, NP-S1+Cur and CRT-NP-S1+Cur, and the synapses in the cerebral cortex and hippocampus were detected by anti-PSD95 and YE2681 antibodies, respectively (A). (B) The fluorescence intensity in (A) was quantitatively analyzed by Image-Pro Plus software (*, P < 0.05, **, P < 0.01, compared with NP control-treated AD mice).
