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. 2017 Sep 14;8(46):81176–81185. doi: 10.18632/oncotarget.20885

Table 3. Associations between decreased expression of E-cadherin and clinicopathological features.

Clinicopathological features Pooled HR 95% CI for HR p value I2 value (%) Model
Lower Upper
Age (≥ 50 vs. < 50) 1.07 0.85 1.36 0.145 41.5 Random
FIGO stage (III, IV vs. I, II) 3.74 2.24 6.23 0.37 0 Fixed
E-cadherin membranous staining (negative vs. positive) 1.47 1.01 2.14 0.78 0 Fixed
Pathologic grade (G3 vs. G1, G2) 1.41 1.01 1.97 0.13 47 Random
Residual tumor (<1cm vs. > 1cm) 2.72 1.99 3.72 0.51 0 Fixed
Surgery (suboptimal vs. optimal) 3.21 1.19 8.67 0.074 68.7 Random
Chemotherapy (non-paclitaxel vs. paclitaxel) 1.31 0.31 5.57 <0.01 90.4 Random
Lymphatic metastasis (negative vs. positive) 1.40 0.63 3.10 0.01 86.6 Random