Table 3. Eight candidate microRNAs displaying higher levels in HCC cases with positive AFB1 than controls with positive AFB1 in the discovery cohort.
miRNA | Average Ct value | CV | Fold Change | |||
---|---|---|---|---|---|---|
No. | Controls | Cases | Controls | Cases | ||
01 | miR-7-2-3p | 28.62 | 22.03 | 0.0171 | 0.0236 | 10.71 |
02 | miR-4651 | 28.12 | 12.96 | 0.0238 | 0.0694 | 4071.41 |
03 | miR-127-3p | 26.16 | 21.62 | 0.0317 | 0.0167 | 10.31 |
04 | miR-192-5p | 28.99 | 17.57 | 0.0328 | 0.0102 | 302.61 |
05 | miR-382-5p | 28.91 | 21.91 | 0.0090 | 0.0050 | 14.19 |
06 | miR-10b-5p | 28.77 | 17.77 | 0.0115 | 0.0523 | 227.75 |
07 | miR-532-3p | 26.66 | 22.83 | 0.0154 | 0.0197 | 3.57 |
08 | miR-16-5p | 25.67 | 20.32 | 0.0105 | 0.0305 | 4.54 |
Abbreviations: HCC, hepatocellular carcinoma, AFB1, aflatoxin B1; CV, coefficient of variation.