Table 2. Summary of neuropsychologic assessments.
| Tests | Patients Treated With Chemotherapy (CT)(n =19) |
Healthy Controls (HC)(n=11) |
Group Time Interaction With Repeated Measures ANOVA | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| t1 | t2 | Paired t-test | t1 | t2 | Paired t-test | F | P | |||||
| mean | SD | mean | SD | mean | SD | mean | SD | |||||
| AVLT | 31.42 | 8.051 | 26.53 | 8.650 | 0.016* | 29.64 | 11.138 | 30.00 | 11.533 | 0.542 | 4.554 | 0.042* |
| short term | 10.53 | 1.982 | 10.00 | 2.582 | 0.340 | 11.55 | 2.659 | 12.00 | 2.966 | 0.138 | 1.746 | 0.197 |
| long term | 8.74 | 3.070 | 8.11 | 3.430 | 0.383 | 8.82 | 3.710 | 9.00 | 3.899 | 0.506 | 0.725 | 0.402 |
| recognition | 12.16 | 3.516 | 8.42 | 3.761 | 0.001* | 9.27 | 5.287 | 9.00 | 5.177 | 0.341 | 8.076 | 0.008* |
| Digit Symbol | 52.84 | 15.770 | 51.26 | 15.202 | 0.450 | 54.64 | 14.080 | 55.55 | 14.123 | 0.264 | 0.809 | 0.376 |
| Digit Span forward |
6.05 | 1.353 | 5.89 | 1.629 | 0.546 | 6.36 | 1.286 | 6.73 | 1.191 | 0.167 | 1.825 | 0.188 |
| backward | 5.05 | 1.026 | 5.11 | 1.761 | 0.848 | 5.91 | 1.514 | 5.73 | 1.272 | 0.341 | 0.375 | 0.545 |
| MOCA | 25.95 | 3.659 | 25.58 | 3.878 | 0.414 | 26.91 | 2.982 | 27.00 | 2.793 | 0.724 | 0.561 | 0.460 |
| FACT-COG | 106.21 | 23.220 | 89.00 | 25.126 | 0.003* | 117.18 | 7.808 | 119.64 | 7.103 | 0.036* | 8.896 | 0.006* |
| CogPCI | 57.16 | 13.937 | 46.11 | 15.613 | 0.001* | 63.82 | 6.369 | 64.91 | 5.431 | 0.210 | 10.094 | 0.004* |
| CogQOL | 12.21 | 4.650 | 12.05 | 4.288 | 0.888 | 14.55 | 2.544 | 15.73 | 0.647 | 0.168 | 0.717 | 0.404 |
| CogOth | 14.26 | 3.177 | 12.21 | 4.276 | 0.070 | 15.09 | 1.868 | 15.45 | 1.293 | 0.341 | 2.823 | 0.104 |
| CogPCA | 22.58 | 4.598 | 18.63 | 6.335 | 0.019* | 23.73 | 3.977 | 23.55 | 3.698 | 0.640 | 3.354 | 0.078 |
* Statistically significant; ANOVA: analysis of variance; AVLT: Auditory Verbal Learning Test; MOCA: Montreal Cognitive Assessment; FACT-COG: Functional Assessment of Cancer Therapy-Cognitive Function; CogPCI: perceived cognitive impairments; CogQOL: impact of perceived impairments on quality of life; CogOth: comments from others; CogPCA: perceived cognitive abilities; SD: standard deviation.