Table 2. Frequency of adverse events.
| Toxicity Grade | 0 | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|---|
| Hematologic | ||||||
| Anemia | 1 | 38 | 29 | 4 | 0 | 0 |
| Reduced platelet count | 16 | 38 | 15 | 3 | 0 | 0 |
| Reduced neutrophil count | 7 | 0 | 25 | 32 | 8 | 0 |
| Non-hematologic | ||||||
| Nausea | 25 | 33 | 9 | 5 | 0 | 0 |
| Vomiting | 47 | 16 | 7 | 2 | 0 | 0 |
| Anorexia | 34 | 29 | 7 | 2 | 0 | 0 |
| Diarrhea | 59 | 10 | 1 | 2 | 0 | 0 |
| Febrile neutropenia | 69 | 2 | 0 | 1 | 0 | 0 |
| Abdominal pain | 37 | 27 | 6 | 2 | 0 | 0 |
| Asthenia | 28 | 33 | 10 | 1 | 0 | 0 |
| Elevated ALT | 49 | 20 | 2 | 1 | 0 | 0 |
| Elevated AST | 44 | 24 | 3 | 1 | 0 | 0 |
| T bilirubin | 62 | 4 | 1 | 5 | 0 | 0 |
| Pneumonitis | 70 | 0 | 0 | 1 | 0 | 1 |
| Edema | 60 | 10 | 2 | 0 | 0 | 0 |
| Myalgia | 54 | 11 | 7 | 0 | 0 | 0 |
| Dizziness | 55 | 13 | 3 | 1 | 0 | 0 |
| Headache | 56 | 13 | 3 | 0 | 0 | 0 |