Figure 1. Axial T1-weighted contrast-enhanced (top row) and T2-FLAIR images (bottom row) in Patient 5.

This patient had a left temporal glioblastoma illustrated as a cystic lesion with a rim of contrast-enhancement. This cavity was stable throughout the serial MR examinations and T2-FLAIR showed decreased edema. Four smaller contrast-enhancing lesions (out-of-field) were also stable throughout the study in the left temporal and left periventricular region. After cycle 7, a small new contrast-enhancing lesion appeared in the left temporal region and represented progressive disease.